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TIGR Moffitt Large Scale National Cancer Institute
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  • Chen T, Yang I, Irby R, Shain KH, Wang HG, Quackenbush J, Coppola D, Cheng JQ, Yeatman TJ, Regulation of caspase expression and apoptosis by adenomatous polyposis coli Cancer Res. Aug 1;63(15):4368-74 2003.
    Supporting Materials

  • Deepak Agrawal1, Tingan Chen2, Rosalyn Irby2, John Quackenbush5, Ann F. Chambers4, Marianna Szabo3, Domenico Coppola3, Timothy J. Yeatman2 Osteopontin Identified as Lead Marker of Colon Cancer Progression Using Expression Profiling on Pooled Samples
    1Departments of Cell Biology, 2Surgery, 3Pathology and Interdisciplinary Oncology, H. Lee Moffitt Cancer Center, University of South Florida, Tampa, FL, USA 4London Regional Cancer Centre, University of Western Ontario, Ontario, Canada 5The Institute for Genomic Research, Rockville, MD, USA

  • We have developed a clone set and microarrays containing 19,200 cDNA clones representing nearly 16,000 unique genes. These have been used in a study of cell line models of tumor metastasis which was described in:

    Hegde, P., Qi, R., Gaspard, R., Abernathy, K., Dharap, S., Earle-Hughes, J., Gay, C., Nwokekeh, N.U., Chen, T., Saeed, A.I., Sharov, V., Lee, N.H, Yeatman, T.J., and Quackenbush, J., Identification of tumor markers in models of human colorectal cancer using a 19,200 element cDNA microarray. Cancer Res. Nov 1, 2001.
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